From Dr. Roseann Capanna-Hodge, Ed.D.
Running on empty by 3 p.m. isn’t a willpower problem.
Every cell in your brain and body relies on NAD+ to make energy, and NAD+ tends to decline as we age.[6] NMN Brain gives your body 1,000 mg of NMN, its direct building block, plus the methylation support most NMN formulas leave out.*
- 1,000 mg of NMN in every 2-capsule serving: the direct precursor your cells use to make NAD+*
- Paired with TMG and methylated B12 + folate, because NMN shouldn’t have to work alone*
- Science-plain and adults-only, with a 180-day money-back guarantee
Free US shipping · 180-day money-back guarantee
Sound familiar?
You’re not imagining it. And it’s not a character flaw.
You wake up already behind. Coffee carries you to lunch. Somewhere around 3 p.m. the words stop coming, you reread the same email three times, and there’s still pickup, dinner and bedtime ahead. Then at 11 p.m. you’re exhausted and somehow wide awake. Tired but wired.
Most women try the obvious fixes first: more coffee, a women’s multivitamin, a menopause blend, the earlier bedtime that never quite happens. Some of it helps a little. A lot of it just borrows energy from later in the day.
What those fixes rarely address is simple: energy is made, not willed. Every cell in your body, including every brain cell, turns food into usable energy with help from a molecule called NAD+.
What you feel on the surface
- The afternoon crash that coffee no longer fixes
- Reading the same paragraph twice
- Tired at night, but your mind won’t power down
- Feeling like you run the whole house on fumes
What’s happening underneath
- NAD+ helps your mitochondria turn food into ATP, your cells’ energy currency
- Research suggests NAD+ can decline significantly with age, by some estimates roughly half between our 40s and 60s[6]
- Stress, short sleep and a full plate keep demand high
An illustration of the idea, not a diagnosis. Fatigue has many causes; talk with your doctor if it’s persistent.
Researchers are still studying exactly what that decline means for how we feel day to day. Nobody honest can promise you a miracle. But supporting healthy NAD+ levels is one of the most studied, most promising places to start.*
Why she made it
Meet Dr. Roseann Capanna-Hodge
For more than 30 years, Dr. Roseann has worked with brains and nervous systems for a living. She has reviewed over 10,000 QEEG brain maps. You may know her from the Dysregulated Kids podcast or her new book, The Dysregulated Kid.
Her work comes down to one idea: regulate first, then everything else works better. It’s what she teaches parents about their kids. It’s also what she kept seeing in the moms sitting across from her, running the whole household on empty.
NAD+ support is part of her own daily routine; she takes NAD+ by injection. She is also candid that she doesn’t love oral NAD+ pills, and most women don’t have a clinic around the corner. So she wanted an oral option she would actually stand behind: the right precursor, a meaningful dose, and the cofactors that help your body use it.* That became NMN Brain.
The science, plainly
How NMN becomes energy your cells can use
NAD+ itself is a large, fragile molecule that doesn’t survive digestion well,[6] which is why swallowing NAD+ is a tough road. NMN is different. It is the direct precursor, one enzymatic step away from NAD+.[6]
You take 2 capsules
1,000 mg of NMN each morning.
NMN is absorbed
It sits one enzymatic step away from NAD+.
Cells make NAD+
Human trials show oral NMN raises NAD+ in the blood.[2,3,5]
NAD+ goes to work
Helping mitochondria turn food into ATP, and supporting enzymes involved in cell upkeep.*
A simplified model of a well-established pathway. Blood NAD+ is what the human trials measured.
What human studies show, and what they don’t
Raises NAD+
In randomized, placebo-controlled human trials, oral NMN raised blood NAD+ levels.[2,3,5]
Studied in women
In a 10-week trial in postmenopausal women, NMN improved muscle insulin sensitivity.[1]
Daytime function and sleep
A 2024 clinical trial found NMN was linked to better sleep quality and maintained physical function in older adults.[5]
Well tolerated
Doses at or above the 1,000 mg in NMN Brain were well tolerated in human trials lasting several weeks.[4,8]
Not yet shown
No human trial has tested NMN directly for brain fog or memory. We won’t pretend otherwise.
The honest takeaway
Strong evidence that NMN raises NAD+. Promising, still-growing evidence about what that means for how you feel.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
What’s inside
Why NMN Brain doesn’t ask NMN to work alone
Most NMN supplements stop at NMN. Dr. Roseann wanted the supporting cast in the same capsule.

NMN (nicotinamide mononucleotide)
The direct building block of NAD+. 1,000 mg sits within the range studied in human clinical trials for safety and NAD+ elevation.[3,4,8]
TMG, for methylation
When your body processes NMN, it uses up methyl groups. TMG is a methyl donor, included to help support your methylation processes alongside NMN, and it is well studied for supporting healthy homocysteine levels.*[7]
Methylcobalamin and 5-MTHF
The active forms of vitamin B12 and folate, so your body doesn’t have to convert them first. They round out the methylation support.*
Side by side
NMN Brain vs. typical NMN
| What to check | NMN Brain | Typical NMN product |
|---|---|---|
| NMN per serving | 1,000 mg | Often 250 to 500 mg |
| TMG for methylation | Included | Usually sold separately |
| Methylated B12 + folate | Included | Rarely included |
| Formulated with a named clinician | Yes, Dr. Roseann | Usually not |
| Money-back guarantee | 180 days | Often 14 to 60 days |
| Adults-only, pregnancy and nursing exclusions stated | Yes | Varies |
Based on a review of popular NMN products in September 2026. Formulas change, so check any label you compare.
Questions, answered
Before you choose
How do I take NMN Brain?
Two capsules each morning with water. One bottle holds 60 capsules, a 30-day supply. Take it every day; consistency matters more than the exact time.
How soon will I notice anything?
Honestly, it varies. The human trials ran 6 to 12 weeks,[2,3,5] and it makes sense to give NMN two to three months before you judge it. Everyone responds differently, and some people notice nothing obvious. That’s why the guarantee is 180 days, not 30.
Is NMN safe?
In human trials, NMN was well tolerated at doses up to about 1,200 to 1,250 mg a day for several weeks, without serious adverse events.[4,8] Mild stomach upset or headache is occasionally reported. Multi-year data doesn’t exist yet. If you take medication or have a health condition, check with your doctor first.
Can my kids or teens take it?
No. NMN Brain is for adults 18 and over only.
Can I take it while pregnant or nursing?
No. NMN hasn’t been studied in pregnancy or breastfeeding, so NMN Brain is not for use during either.
Is NMN allowed in supplements?
Yes. In September 2025 the FDA confirmed that NMN is not excluded from the definition of a dietary supplement. Like every supplement, NMN Brain is not “FDA approved”; supplements never are.
Why get more than one bottle?
One bottle lasts 30 days, and the human trials ran 6 to 12 weeks. A 3- or 6-bottle supply lets you give it a fair trial without running out, and 6 bottles cover the full 180 days of your guarantee.
What if it doesn’t work for me?
Then you shouldn’t pay for it. You have 180 days to ask for a refund of your purchase price. [PLACEHOLDER: support contact and final refund terms]
Choose your supply
Choose your NMN Brain supply
Every package ships free in the US and is covered by the 180-day money-back guarantee.
Your 180-day money-back guarantee. Every package is covered. Take NMN Brain for up to 180 days. If you are not happy with it for any reason, contact us for a refund of your purchase price. [PLACEHOLDER: final refund terms]
Each bottle: 60 capsules, a 30-day supply at 2 capsules a day. Checkout link pending; buttons continue to the demo flow. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Her promise
180 days to decide. Not 30.
“I’ve spent my career telling parents the truth, even when it isn’t the easy answer. So here it is: NMN Brain isn’t magic, and no supplement is. It’s the most thoughtful version of this I could put together: the right precursor, a meaningful dose, and the cofactors that help your body use it.
Give it a real trial. If you’re not happy with it for any reason within 180 days, contact our team for a refund of your purchase price. That’s long enough to know.”
Dr. Roseann
Signature set in type until her own is supplied.
A good fit?
Is NMN Brain right for you?
It’s for you if
- You’re an adult whose energy runs out before her day does
- You want science-plain support, not hype or stimulants
- You’re willing to give it two to three months
- You like knowing exactly what’s in your capsules, and why
It’s not for you if
- You’re under 18
- You’re pregnant or nursing
- You want an overnight fix
- You take medication or have a medical condition and haven’t checked with your doctor yet
Choose your supply
Ready when you are
Choose the supply that fits. Six bottles give you the full 180 days your guarantee covers.
Your 180-day money-back guarantee. Every package is covered. Take NMN Brain for up to 180 days. If you are not happy with it for any reason, contact us for a refund of your purchase price. [PLACEHOLDER: final refund terms]
Each bottle: 60 capsules, a 30-day supply at 2 capsules a day. Checkout link pending; buttons continue to the demo flow. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.